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Filtered Search Results
Apexbio Technology LLC Methylthioadenosine 2457-80-9 25mg
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Methylthioadenosine (2457-80-9) is a small-molecule inhibitor targeting high-affinity cyclic AMP phosphodiesterase It is designed to inhibit this enzyme thereby regulating cyclic AMP signaling and related cellular pathways Methylthioadenosine exerts its biological activity primarily through enzyme inhibition In cell-based studies it demonstrates inhibitory activity with a Ki value of 62 M against S49-derived high-affinity cyclic AMP phosphodiesterase Based on these pharmacological properties Methylthioadenosine holds research potential in exploring cellular signaling liver protection and mechanisms underlying hepatic pathologies
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Medchemexpress LLC Galiximab 10mg | 10mg
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Galiximab (IDEC-114) is a primatized monoclonal IgG1 antibody targeting CD80 Galiximab variable regions are primatized and the constant regions are humanized Galiximab induces antibody-dependent cellular cytotoxicity by blocking CD80-CD28 binding Galiximab has antitumor activity and can induce apoptosis in tumor cells Galiximab can be used in the research of relapsed Hodgkin lymphoma and solid tumors[1][2]
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Medchemexpress LLC Tebentafusp 1mg | 1mg
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Tebentafusp (IMCgp100) is a bispecific fusion protein to target gp100 peptide-HLA-A 02 01 (a melanoma-associated antigen) Tebentafusp guides T cells to kill gp100-expressing tumor cells via a high affinity T-cell receptor (TCR) binding domain and an anti-CD3 T-cell engaging domain Tebentafusp leads to inflammatory cytokines and cytolytic proteins production resulting in the direct lysis of tumour cells[1][2]
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Medchemexpress LLC Emunkitug 5mg | 5mg
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HY-P990994 is an TNFRSF1B-targeting IgG1 type humanized antibody the recommed isotype control is Human IgG1 kappa Isotype Control (HY-P99001)[1]
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Medchemexpress LLC Anti-Mouse PD-1 Anti 100mg | 100mg
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Anti-Mouse PD-1 Antibody (RMP1-14) is an anti-mouse PD-1 IgG2a antibody Anti-Mouse PD-1 Antibody (RMP1-14) can be used for the study of colon carcinoma[1]
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Medchemexpress LLC Pumitamig 1mg | 1mg
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Pumitamig is a bispecific antibody that targets both PD-L1 and VEGF-A Pumitamig can be used for the study of solid tumors[1]
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Medchemexpress LLC Emugrobart 10mg | 10mg
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HY-P990993 is an GDF8-targeting IgG1 type humanized antibody the recommed isotype control is Human IgG1 kappa Isotype Control (HY-P99001)[1]
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Medchemexpress LLC Palverafusp alfa 1mg | 1mg
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Palverafusp alfa is an VEGFA/PDCD1-targeting IgG1 type humanized antibody the recommed isotype control is Human IgG1 kappa Isotype Control (HY-P99001)[1]
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Medchemexpress LLC Vadastuximab 5mg | 5mg
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Vadastuximab (Anti-Human CD33 Recombinant Antibody) is a humanized monoclonal antibody targeting CD33 Vadastuximab can be used to synthesize an ADC compound Vadastuximab talirine[1]
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Apexbio Technology LLC UBP1112 339526-74-8 50mg
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UBP1112 is an antagonist targeting type III metabotropic glutamate (mGlu) receptors a subgroup of G protein-coupled receptors involved in synaptic modulation of excitatory neurotransmission within the central nervous system Structurally UBP1112 interacts specifically with these receptors blocking glutamate binding and subsequently altering downstream signal transduction In neuroscience research UBP1112 serves as an investigative tool for examining receptor-mediated neuronal signaling pathways and for studying pathophysiological mechanisms underlying neurodegenerative conditions
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Medchemexpress LLC Mibavademab 1mg | 1mg
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Mibavademab is a CHO-expressed humanized antibody that targets LEPR/CD295 Mibavademab is equipped with a huIgG4SP heavy chain and a hu light chain with a predicted molecular weight (MW) of 145 58 kDa The isotype control for Mibavademab can be referenced as Human IgG4 kappa Isotype Control (HY-P99003)
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Medchemexpress LLC Briakinumab 10mg | 10mg
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Briakinumab (ABT-874) is a fully human anti-IL-12/23p40 monoclonal antibody Briakinumab targets and neutralizes IL-12 and IL-23 Briakinumab can be used for the research of rheumatoid arthritis inflammatory bowel disease and multiple sclerosis[1]
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Medchemexpress LLC Fetrastobart 1mg | 1mg
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SGN-PDL1V Antibody is a PD-L1 targeting antibody SGN-PDL1V Antibody can be used for synthesis of ADC SGN-PDL1V (HY-171821)[1]
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Apexbio Technology LLC DiscoveryProbe™ Metabolism-related Compound Library Plus 100uL/well(10 mM solution),96 Well Deep Well Plate
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DiscoveryProbe Metabolism-related Compound Library contains 493 biologically active small molecules targeting diverse cellular metabolic processes These compounds are well-characterized with documented bioactivity data from agencies including FDA and EMA approvals Designed specifically for research in cellular metabolism this library encompasses inhibitors agonists or modulators aimed at metabolically relevant targets such as dehydrogenases PPAR receptors HMG-CoA reductase IDO enzymes and heat shock proteins (HSPs) Representative compounds include PPAR agonists IDO inhibitors and known HMG-CoA reductase modulators enabling researchers to dissect metabolic pathways screen for novel drug targets and explore mechanisms underlying metabolic diseases
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Medchemexpress LLC Anti-ANGPTL4 Antibod 5mg | 5mg
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Anti-ANGPTL4 Antibody is a CHO expressed human antibody targeting ANGPTL4 Anti-ANGPTL4 Antibody has a huIgG1-type heavy chain and a hu -type light chain with a predicted molecular weight (MW) of 150 kDa An isotype control for Anti-ANGPTL4 Antibody can be found in Human IgG1 kappa Isotype Control (HY-P99001)
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